What effects does coffee have on the liver? This is what science says.

Coffee is one of the world’s most consumed beverages, with about two billion cups enjoyed daily. Its widespread popularity has sparked growing scientific interest, particularly regarding its effects on liver health.

The liver plays a crucial role in detoxification, metabolism, and bile production. Research shows that coffee components like caffeine and chlorogenic acids may offer protective effects. Caffeine can reduce liver inflammation and fat accumulation, while chlorogenic acids help prevent oxidative damage.

Moderate coffee consumption—two to three cups daily—has been linked to reduced progression of non-alcoholic fatty liver disease (NAFLD) and fibrosis. Studies suggest coffee inhibits hepatic stellate cells, which contribute to scarring and chronic inflammation in the liver.

Regular coffee drinkers may also have a lower risk of developing cirrhosis, with some studies showing up to a 40% risk reduction. While promising, coffee cannot replace medical treatment for existing liver conditions.

For people with viral hepatitis (B or C), research indicates that coffee might slow fibrosis progression and enhance treatment response. Some studies report improved liver markers and reduced complications with three or more cups per day.

Coffee may also play a role in preventing liver cancer. A meta-analysis found that each additional cup of coffee may reduce the risk of hepatocellular carcinoma. This benefit likely stems from coffee’s anti-inflammatory and antioxidant properties.

Filtered coffee appears more beneficial than unfiltered types. Caffeinated coffee shows stronger liver-protective effects, though decaf still offers advantages.

Most people can safely enjoy two to four cups daily. However, those with liver disease, pregnancy, or sensitivity to caffeine should consult a doctor.